treatment related acute promyelocytic leukemia (t-apml) in breast cancer survivor treated with anthracycline based chemotherapy: rare case report

Treatment related acute promyelocytic leukemia (t-APML) in breast cancer survivor treated with anthracycline based chemotherapy: rare case report

Treatment related acute myeloid leukemia (t-AML) is well documented phenomenon after chemotherapy. In this subgroup of patients acute promyelocytic leukemia (APML) due to delayed complication of using anthracycline is very rare occurrence. Very few cases are reported in world literature. We are reporting a rare case of occurrence of t-APML in cured breast cancer patient treated with doxorubicin...

Occurrence of Secondary Acute Myeloid Leukemia in a Patient with Breast Cancer after Chemotherapy

CD34(+) therapy-related acute promyelocytic leukemia in a patient previously treated for breast cancer.

Therapy-related acute myeloid leukemia (AML) is a long term complication of chemotherapy for a variety of cancers. In most cases, the marrow demonstrates high risk cytogenetics and the prognosis is poor. In a minority of patients "good risk" cytogenetics, including t(15;17)(q22;q12), are seen and the patient's prognosis is similar to those who have de novo disease. Currently we present a patien...

Acute promyelocytic leukemia can be treated successfully without cytotoxic chemotherapy.

In their scholarly article, Dr. Park and Dr. Tallman review the important clinical trials for treating patients with APL reported over the last two decades and argue the case for further reduction and perhaps elimination of conventional cytotoxic chemotherapy in the frontline treatment of this disease.[1] Treatment of APL has evolved during the last several decades following the demonstration t...

adjuvant chemotherapy of early stage breast cancer in community-based cancer treatment fields: cmf compared with anthracycline/taxane-based regimens

introduction: mortality rate of breast cancer has been fallen in recent years. combination of cyclophosphamide, methotrexate, and 5-fluorouracil(cmf), as a pioneer of adjuvant chemotherapy of breast cancer, and later introduced anthracycline/taxane(a/t)-based regimens have both produced favorable outcomes in early-stage breast cancer. the current study, aimed to evaluate the probably different ...

Relapsed acute promyelocytic leukemia in a hemodialysis-dependent patient treated with arsenic trioxide: a case report

UNLABELLED INTRODUCTION In the relapsed setting, arsenic trioxide remains the backbone of treatment. Scant literature exists regarding treatment of relapsed acute promyelocytic leukemia in patients with renal failure. To the best of our knowledge we are the first to report a safe and effective means of treatment for relapsed acute promyelocytic leukemia in the setting of advanced renal failu...